South Carolina Multistate Pharmacy Jurisprudence Examination (MPJE) Practice Exam

What are the maximum limits for C3 codeine?

1. 100 mg/100 mL, 50 g, 25 mg/dose

2. 200 mg/100 mL, 100 g, 90 mg/dose

3. 300 mg/100 mL, 150 g, 100 mg/dose

4. 400 mg/100 mL, 200 g, 120 mg/dose

The correct answer is: 200 mg/100 mL, 100 g, 90 mg/dose

The maximum limits for codeine in Schedule III controlled substances are indeed 200 mg per 100 mL or per 100 g, along with 90 mg per single dosage unit. This aligns with the established regulations which classify compounds containing codeine based on their concentrations and dosages, as stipulated by the Controlled Substances Act. The limit of 200 mg per 100 mL or 100 g allows for the formulation of liquid preparations that enable practical use in clinical settings while maintaining control over misuse potential. Similarly, the per-dose limit of 90 mg ensures that each individual prescription remains within acceptable risk parameters for both therapeutic efficacy and safety. Understanding these limits is crucial for pharmacists as it informs both the dispensing practices and the obligations to comply with state and federal regulations regarding controlled substances. This knowledge also aids in educating patients about their medications, ensuring they receive prescriptions that are both legal and effective for their treatment needs.