South Carolina Multistate Pharmacy Jurisprudence Examination (MPJE) Practice Exam

What is a common class of drugs that require MedGuides?

1. Antidepressants

2. Topical steroids

3. Antihistamines

4. Insulin

The correct answer is: Antidepressants

MedGuides are required for certain medications that pose a significant risk of serious and sometimes fatal adverse effects, where patient awareness can help minimize risks. Antidepressants are notably included in this category primarily due to the observed risk of suicidal thoughts and behaviors, particularly in children, adolescents, and young adults. As a result, the FDA mandates that specific information about these risks be provided to patients through MedGuides, ensuring they are informed about potential serious side effects before starting the medication. While topical steroids, antihistamines, and insulin may have their own safety profiles and usage considerations, they do not typically fall under the category of medications that require a MedGuide. This specific requirement for antidepressants underscores the importance of providing patients with information that can lead to better treatment outcomes and increased safety when using potentially high-risk medications.