South Carolina Multistate Pharmacy Jurisprudence Examination (MPJE) Practice Exam

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What is the storage limit for codeine in a C3 formulation?

200 mg/100 mL
1.8 g/100 mL
300 mg/15 dosage units
500 mg/100 mL

The correct answer is: 1.8 g/100 mL

In South Carolina, as well as federally, the storage limit for codeine in a Schedule III (C3) formulation allows for a maximum of 1.8 grams of codeine per 100 mL of liquid formulation. This regulation is in place to control the distribution and potential misuse of controlled substances while still allowing for their legitimate medical use. Understanding the specifics of the scheduling aids in ensuring compliance with both state and federal drug laws. The limit set at 1.8 g/100 mL reflects the intended use of codeine in combination medications, which might include cough syrups or other formulations that require lower doses to avoid abuse potential. This particular regulation is crucial for pharmacies and healthcare providers to monitor, as surpassing this limit could lead to violations of the Controlled Substances Act and state pharmacy laws. Keeping informed about such storage limits helps in maintaining proper inventory management and regulatory compliance in practice settings.