South Carolina Multistate Pharmacy Jurisprudence Examination (MPJE) Practice Exam

Which describes the dependence status of Schedule III substances?

1. High physical dependence, low psychological dependence

2. Low-moderate physical dependence, high psychological dependence

3. No physical dependence, high psychological dependence

4. High physical dependence, high psychological dependence

The correct answer is: Low-moderate physical dependence, high psychological dependence

The dependence status of Schedule III substances is characterized by low to moderate physical dependence and high psychological dependence. This classification reflects the potential for individuals to develop a psychological craving for these substances, which can lead to misuse and potential addiction. Schedule III drugs, such as certain anabolic steroids and products containing less than 90 mg of codeine per dosage unit, have a lower potential for abuse compared to substances in Schedules I and II, which are considered to have a higher risk of severe physical dependence and addiction. The distinction in dependence levels emphasizes the importance of monitoring and regulation of these substances, as while they may not lead to significant physical withdrawal symptoms, psychological dependence can still pose substantial risks for misuse. This understanding is crucial for pharmacists and healthcare providers when prescribing and counseling patients on the use of Schedule III medications.