South Carolina Multistate Pharmacy Jurisprudence Examination (MPJE) Practice Exam

Which of the following drugs is classified as a C2?

1. Hydrocodone

2. Codeine

3. Alprazolam

4. Ibuprofen

The correct answer is: Hydrocodone

Hydrocodone is classified as a Schedule II controlled substance, which is indicated by the designation C2. Schedule II drugs are those that have a high potential for abuse, have a currently accepted medical use in treatment in the United States, and may lead to severe psychological or physical dependence. Hydrocodone is commonly prescribed for the management of pain and is often found in combination with other analgesics, but its classification reflects concerns about the potential for misuse and addiction. This stringent classification requires specific prescribing practices to regulate its distribution and use. In contrast, codeine, while it can be a Schedule II when in certain high doses, is often classified as a Schedule III substance when in combination with other medications, indicating a lower potential for abuse. Alprazolam is classified as a Schedule IV substance, which has a lower potential for abuse relative to Schedule I, II, and III drugs. Ibuprofen, on the other hand, is an over-the-counter medication and is not classified as a controlled substance at all. Thus, hydrocodone’s designation as a C2 drug is aligned with its properties and prescription regulations within controlled substance laws.